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ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $42 | In Stock | |
5 mg | $68 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $198 | In Stock | |
50 mg | $372 | In Stock | |
100 mg | $556 | In Stock | |
500 mg | $1,220 | In Stock | |
1 mL x 10 mM (in DMSO) | $75 | In Stock |
Description | ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM). |
Targets&IC50 | M5 mAChR (rat):610 nMÂ , M5 mAChR (human):190 nM |
Alias | ML-380, ML 380 |
Molecular Weight | 494.53 |
Formula | C23H25F3N4O3S |
Cas No. | 1627138-52-6 |
Smiles | CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 |
Relative Density. | 1.388 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (181.99 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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