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Trimethobenzamide hydrochloride
🥰Excellent
Catalog No. T5009Cas No. 554-92-7
Alias Tribenzagan Hydrochloride, Ro 2-9578
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
Trimethobenzamide hydrochloride
🥰Excellent
Purity: 100%
Catalog No. T5009Alias Tribenzagan Hydrochloride, Ro 2-9578Cas No. 554-92-7
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $54 | In Stock | |
| 100 mg | $81 | In Stock | |
| 200 mg | $108 | In Stock | |
| 500 mg | $166 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. |
| In vitro | Trimethobenzamide, a (non-phenothiazine) benzamide antiemetic, centrally blocks D2 receptors, inhibiting the medullary chemoreceptor trigger zone by obstructing emetic impulses to the vomiting center. |
| In vivo | Trimethobenzamide exhibits an oral bioavailability ranging from 60% to 100%, with a peak time of approximately 45 minutes post-oral administration. When administered intramuscularly (I.M.), the peak time is around 30 minutes. |
| Alias | Tribenzagan Hydrochloride, Ro 2-9578 |
| Molecular Weight | 424.92 |
| Formula | C21H29ClN2O5 |
| Cas No. | 554-92-7 |
| Smiles | Cl.COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1 |
| Relative Density. | 1.131g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (235.34 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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