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Viloxazine

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Catalog No. T60325Cas No. 46817-91-8
Alias Viloxazin, Emovit

Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].

Viloxazine

Viloxazine

🥰Excellent
Purity: 99.8%
Catalog No. T60325Alias Viloxazin, EmovitCas No. 46817-91-8
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].
Pack SizePriceAvailabilityQuantity
1 mg$195In Stock
5 mg$440In Stock
10 mg$648In Stock
25 mg$987In Stock
50 mg$1,390In Stock
100 mg$1,870In Stock
500 mg$3,730In Stock
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Purity:99.8%
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Product Introduction

Bioactivity
Description
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].
Targets&IC50
5-HT2C:32 μM(EC50), 5-HT2B:27 μM
In vivo
Viloxazine (1-16 mg/kg; spinal rat) stimulated the hind limb flexor reflex in the dose-dependent manner.[3]
AliasViloxazin, Emovit
Chemical Properties
Molecular Weight237.29
FormulaC13H19NO3
Cas No.46817-91-8
SmilesO(CC1CNCCO1)C2=C(OCC)C=CC=C2
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (252.86 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2143 mL21.0713 mL42.1425 mL210.7126 mL
5 mM0.8429 mL4.2143 mL8.4285 mL42.1425 mL
10 mM0.4214 mL2.1071 mL4.2143 mL21.0713 mL
20 mM0.2107 mL1.0536 mL2.1071 mL10.5356 mL
50 mM0.0843 mL0.4214 mL0.8429 mL4.2143 mL
100 mM0.0421 mL0.2107 mL0.4214 mL2.1071 mL

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