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CP-809101 hydrochloride

Catalog No. T10871Cas No. 1215721-40-6

CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist with pEC50 values of 9.96 for human 5-HT2C, 7.19 for 5-HT2B, and 6.81 for 5-HT2A receptors.

CP-809101 hydrochloride

CP-809101 hydrochloride

Purity: 99.50%
Catalog No. T10871Cas No. 1215721-40-6
CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist with pEC50 values of 9.96 for human 5-HT2C, 7.19 for 5-HT2B, and 6.81 for 5-HT2A receptors.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
5 mg$75In Stock
10 mg$109In Stock
25 mg$247In Stock
50 mg$455In Stock
100 mg$686In Stock
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Purity:99.50%
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Product Introduction

Bioactivity
Description
CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist with pEC50 values of 9.96 for human 5-HT2C, 7.19 for 5-HT2B, and 6.81 for 5-HT2A receptors.
Targets&IC50
5-HT2B:7.19(pEC50 for human), 5-HT2C:9.96(pEC50 for human), 5-HT2A:6.81(pEC50 for human)
In vitro
CP-809101 is a potent, functionally selective 5-HT2C agonist that displays approximately 100% efficacy in vitro[4].
In vivo
Similar to currently available antipsychotic drugs, CP-809101 dose-dependently inhibited conditioned avoidance responding (CAR, ED50 = 4.8 mg/kg, sc). CP-809101 antagonized both PCP- and d-amphetamine-induced hyperactivity with ED50 values of 2.4 and 2.9 mg/kg (sc), respectively, and also reversed an apomorphine induced-deficit in prepulse inhibition. At doses up to 56 mg/kg, CP-809101 did not produce catalepsy. CP-809101 was inactive in two animal models of antidepressant-like activity, the forced swim test, and learned helplessness[4].
Chemical Properties
Molecular Weight341.24
FormulaC15H18Cl2N4O
Cas No.1215721-40-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 20 mg/mL (58.61 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.9305 mL14.6524 mL29.3049 mL146.5244 mL
5 mM0.5861 mL2.9305 mL5.8610 mL29.3049 mL
10 mM0.2930 mL1.4652 mL2.9305 mL14.6524 mL
20 mM0.1465 mL0.7326 mL1.4652 mL7.3262 mL
50 mM0.0586 mL0.2930 mL0.5861 mL2.9305 mL

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