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Desvenlafaxine
🥰Excellent
Catalog No. T1580Cas No. 93413-62-8
Alias WY 45233 Succinate, O-Desmethylvenlafaxine
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.
Desvenlafaxine
🥰Excellent
Purity: 99.86%
Catalog No. T1580Alias WY 45233 Succinate, O-DesmethylvenlafaxineCas No. 93413-62-8
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $31 | In Stock | |
| 100 mg | $41 | In Stock | |
| 500 mg | $83 | In Stock |
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Purity:99.86%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent. |
| Targets&IC50 | 5-HT:40.2 nM(Ki), Norepinephrine:558.4 nM(Ki) |
| In vitro | In male rats, the oral administration of Desvenlafaxine Succinate penetrates the brain and hypothalamus, significantly increasing extracellular norepinephrine levels. |
| In vivo | Desvenlafaxine Succinate inhibits the neuronal uptake of serotonin (5-HT) and norepinephrine (NE) with IC50 values of 47.3 nM and 531.3 nM, respectively. It exhibits weak binding affinity to human dopamine (DA) transporters at a concentration of 100 μM. |
| Alias | WY 45233 Succinate, O-Desmethylvenlafaxine |
| Molecular Weight | 263.38 |
| Formula | C16H25NO2 |
| Cas No. | 93413-62-8 |
| Smiles | C(CN(C)C)(C1(O)CCCCC1)C2=CC=C(O)C=C2 |
| Relative Density. | 1.115 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 3 mg/mL (11.39 mM) DMSO: 16.67 mg/mL (63.28 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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