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Alizapride hydrochloride

Catalog No. T2574Cas No. 59338-87-3
Alias Alizapride HCl

Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.

Alizapride hydrochloride

Alizapride hydrochloride

Purity: 99.48%
Catalog No. T2574Alias Alizapride HClCas No. 59338-87-3
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
Pack SizePriceAvailabilityQuantity
25 mg$48In Stock
50 mg$71In Stock
100 mg$113In Stock
200 mg$168In Stock
500 mg$283In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.48%
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Product Introduction

Bioactivity
Description
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
In vitro
Intravenous administration of 5 mg/kg Alizapride in rats effectively counteracts the reduction in gastrointestinal motility induced by the given dose of Apomorphine. Alizapride exhibits low toxicity in mice and rats, particularly when administered extragastrically. Following oral or extragastric administration, Alizapride is primarily excreted in its unmodified form; however, approximately 25% of Alizapride undergoes metabolic transformation before excretion.
In vivo
Alizapride contains an N-allyl moiety, which may undergo N-deallylation and/or epoxidation, potentially leading to the formation of chemically reactive metabolites.
AliasAlizapride HCl
Chemical Properties
Molecular Weight351.83
FormulaC16H21N5O2·HCl
Cas No.59338-87-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 50 mg/mL (142.11 mM), Sonication is recommended.
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 40 mg/mL (113.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.8423 mL14.2114 mL28.4228 mL142.1141 mL
5 mM0.5685 mL2.8423 mL5.6846 mL28.4228 mL
10 mM0.2842 mL1.4211 mL2.8423 mL14.2114 mL
20 mM0.1421 mL0.7106 mL1.4211 mL7.1057 mL
50 mM0.0568 mL0.2842 mL0.5685 mL2.8423 mL
100 mM0.0284 mL0.1421 mL0.2842 mL1.4211 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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