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Cariprazine
🥰Excellent
Catalog No. T4577Cas No. 839712-12-8
Alias RGH-188
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
Cariprazine
🥰Excellent
Purity: 99.75%
Catalog No. T4577Alias RGH-188Cas No. 839712-12-8
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $47 | In Stock | |
| 2 mg | $72 | In Stock | |
| 5 mg | $110 | In Stock | |
| 10 mg | $189 | In Stock | |
| 25 mg | $333 | In Stock | |
| 50 mg | $497 | In Stock | |
| 100 mg | $693 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $110 | In Stock |
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CitedSelect Batch
Purity:99.75%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
| Targets&IC50 | D2 receptor:0.49 nMÂ , 5-HT1A receptor:2.6 nM, D3 receptor:0.085 nM |
| Alias | RGH-188 |
| Molecular Weight | 427.41 |
| Formula | C21H32Cl2N4O |
| Cas No. | 839712-12-8 |
| Smiles | CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |
| Relative Density. | 1.24 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: Slightly soluble  |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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