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Lumateperone
Catalog No. T21069Cas No. 313368-91-1
Alias ITI722, ITI-007, ITI007, ITI 722
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).
Lumateperone
Catalog No. T21069Alias ITI722, ITI-007, ITI007, ITI 722Cas No. 313368-91-1
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $33 | In Stock | |
| 25 mg | $53 | In Stock | |
| 50 mg | $77 | In Stock | |
| 100 mg | $118 | In Stock |
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CLOZAPINE N-OXIDE
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CitedCLOZAPINE N-OXIDE Cited
T449434233-69-7
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopamine antagonist and selective muscarinic M4 receptor agonist.
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CitedCLOZAPINE N-OXIDE Cited
T449434233-69-7
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CitedCLOZAPINE N-OXIDE Cited
T449434233-69-7
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CitedSelect Batch
Purity:99.77%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM). |
| In vivo | ITI-722 was evaluated in the rat quipazine head twitch model induced by quipazine which is a 5-HT2A agonist, ITI-722 have ED50 values of 0.12 mg/kg. |
| Alias | ITI722, ITI-007, ITI007, ITI 722 |
| Molecular Weight | 393.5 |
| Formula | C24H28FN3O |
| Cas No. | 313368-91-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.93 mg/mL (10 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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