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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $43 | In Stock | |
25 mg | $81 | In Stock | |
50 mg | $135 | In Stock | |
100 mg | $198 | In Stock | |
200 mg | $297 | In Stock | |
500 mg | $491 | In Stock | |
1 mL x 10 mM (in DMSO) | $48 | In Stock |
Description | Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides. |
Alias | Naratriptan HCl, Amerge, Naramig, GR-85548A hydrochloride |
Molecular Weight | 371.93 |
Formula | C17H25N3O2S·HCl |
Cas No. | 143388-64-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 20 mg/mL (53.8 mM) DMSO: 65 mg/mL (174.76 mM), Sonication is recommended. ![]() Ethanol: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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