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Pimethixene
🥰Excellent
Catalog No. T12489Cas No. 314-03-4
Alias Pimetixene, Calmixen
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively).
Pimethixene
🥰Excellent
Purity: 99.1%
Catalog No. T12489Alias Pimetixene, CalmixenCas No. 314-03-4
Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $29 | In Stock | |
| 5 mg | $43 | In Stock | |
| 10 mg | $59 | In Stock | |
| 25 mg | $108 | In Stock | |
| 50 mg | $160 | In Stock | |
| 100 mg | $238 | In Stock | |
| 200 mg | $356 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $48 | In Stock |
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Purity:99.1%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively). |
| Targets&IC50 | 5-HT2C receptor:8.42 (pki), 5-HT1A receptor:7.63 (pki), M2 mAChR:9.38 (pki), D2 receptor:8.19 (pki), 5-HT2A receptor:10.22 (pki), DD4.4 receptor:7.54 (pki), M1 receptor:8.61 (pki), 5-HT2B receptor:10.44 (pki), H1 receptor:10.14 (pki) |
| Alias | Pimetixene, Calmixen |
| Molecular Weight | 293.43 |
| Formula | C19H19NS |
| Cas No. | 314-03-4 |
| Smiles | CN1CCC(CC1)=C1c2ccccc2Sc2ccccc12 |
| Relative Density. | 1.192g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 18.33 mg/ml (62.48 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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