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Ranolazine dihydrochloride

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Purity:100%

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COA LCMS HNMR

Ranolazine dihydrochloride

Catalog No. T0207Cas No. 95635-56-6

Ranolazine dihydrochloride (Ranolazine 2HCl) , an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and do not affect blood pressure or heart rate.

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Pack Size	Price	Availability
50 mg	$44	In Stock
100 mg	$62	In Stock
200 mg	$97	In Stock
500 mg	$158	In Stock
1 g	$217	In Stock
1 mL x 10 mM (in DMSO)	$63	In Stock

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Product Introduction

Bioactivity

Description	Ranolazine dihydrochloride (Ranolazine 2HCl) , an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and do not affect blood pressure or heart rate.
Targets&IC50	INa:6 μM (IC50), IKr:12 μM (IC50)
Alias	RS 43285, Ranolazine 2HCl

Chemical Properties

Molecular Weight	500.46
Formula	C24H35Cl2N3O4
Cas No.	95635-56-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45 mg/mL (89.92 mM)

H2O: 50.1 mg/mL (100 mM)

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.9982 mL	9.9908 mL	19.9816 mL	99.9081 mL
5 mM	0.3996 mL	1.9982 mL	3.9963 mL	19.9816 mL
10 mM	0.1998 mL	0.9991 mL	1.9982 mL	9.9908 mL
20 mM	0.0999 mL	0.4995 mL	0.9991 mL	4.9954 mL
50 mM	0.0400 mL	0.1998 mL	0.3996 mL	1.9982 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0200 mL	0.0999 mL	0.1998 mL	0.9991 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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