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RU 24969 free base

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Catalog No. T8593Cas No. 66611-26-5
Alias 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.

RU 24969 free base

RU 24969 free base

🥰Excellent
Purity: 99.69%
Catalog No. T8593Alias 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleCas No. 66611-26-5
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
Pack SizePriceAvailabilityQuantity
5 mg$56In Stock
10 mg$85In Stock
50 mg$276In Stock
100 mg$412In Stock
1 mL x 10 mM (in DMSO)$66In Stock
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Purity:99.69%
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Product Introduction

Bioactivity
Description
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
Targets&IC50
5-HT1A receptor:2.5 nM (Ki), 5-HT1B receptor:0.38 nM (Ki)
Alias5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Chemical Properties
Molecular Weight228.29
FormulaC14H16N2O
Cas No.66611-26-5
SmilesCOC1=CC2=C(NC=C2C2=CCNCC2)C=C1
Relative Density.1.174 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (131.41 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3804 mL21.9020 mL43.8039 mL219.0197 mL
5 mM0.8761 mL4.3804 mL8.7608 mL43.8039 mL
10 mM0.4380 mL2.1902 mL4.3804 mL21.9020 mL
20 mM0.2190 mL1.0951 mL2.1902 mL10.9510 mL
50 mM0.0876 mL0.4380 mL0.8761 mL4.3804 mL
100 mM0.0438 mL0.2190 mL0.4380 mL2.1902 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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