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Eribulin mesylate

Catalog No. T13687 CAS 441045-17-6

Synonyms: B1939 mesylate, ER-086526 mesylate, E7389 mesylate

Eribulin mesylate (E7389 mesylate) (E7389 mesylate) inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Eribulin mesylate (E7389 mesylate) is a microtubule targeting agent that is used in the treatment of metastatic breast cancer.

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Eribulin mesylate, CAS 441045-17-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 430.00
5 mg	In stock	$ 597.00
10 mg	In stock	$ 828.00
25 mg	In stock	$ 1,230.00
50 mg	In stock	$ 1,660.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	B1939 mesylate, ER-086526 mesylate, E7389 mesylate
Molecular Weight	826
Formula	C41H63NO14S
CAS No.	441045-17-6

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 98 mg/mL (118.64 mM)

DMSO: 98 mg/mL (118.64 mM)

References and Literature

1. Okouneva, T., et al., Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase. Mol Cancer Ther, 2008. 7(7): p. 2003-11. 2. Smith, J.A., et al., Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability. Biochemistry, 2010. 49(6): p. 1331-7. 3. Towle, M.J., et al., Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res, 2011. 71(2): p. 496-505.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Cancer Approved Drug Library Cytoskeletal Signaling Pathway Compound Library Anti-Breast Cancer Compound Library FDA-Approved Drug Library Anti-Cancer Compound Library FDA-Approved & Pharmacopeia Drug Library Approved Drug Library ReFRAME Related Library Macrocyclic Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Eribulin mesylate 441045-17-6 Apoptosis Cytoskeletal Signaling Others Microtubule Associated E7389 Mesylate ER 086526 E-7389 Eribulin metastatic B1939 Inhibitor B1939 mesylate inhibit E 7389 Mesylate breast Microtubule/Tubulin cancer B 1939 Mesylate E7389 B 1939 B-1939 Mesylate B1939 Mesylate B-1939 Eribulin Mesylate microtubule E-7389 Mesylate E 7389 ER-086526 ER086526 Mesylate ER 086526 Mesylate ER-086526 mesylate ER-086526 Mesylate ER086526 E7389 mesylate inhibitor

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