Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 43.00 | |
25 mg | In stock | $ 63.00 | |
50 mg | In stock | $ 97.00 | |
100 mg | In stock | $ 166.00 | |
200 mg | In stock | $ 282.00 | |
500 mg | In stock | $ 488.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 38.00 |
Description | Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients. |
Targets&IC50 | β1-adrenoceptor:0.8 nM |
Cell Research | Cells are exposed to different concentrations of Nebivolol (10-7~10-5 M) for 1, 2, 4, 7 and 14 days. Cell proliferation is analyzed by bromodeoxyuridine (BrdU) incorporation, and cell apoptosis is detected by PI or annexin V staining.(Only for Reference) |
Synonyms | R 065824 hydrochloride, Nebivolol HCl, R-65824 |
Molecular Weight | 441.9 |
Formula | C22H25F2NO4·HCl |
CAS No. | 152520-56-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 4.4 mg/mL (10 mM)
DMSO: 44.2 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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