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SB-200646

Catalog No. T8357Cas No. 143797-63-1

SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor

SB-200646

SB-200646

Purity: 99.61%
Catalog No. T8357Cas No. 143797-63-1
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
Pack SizePriceAvailabilityQuantity
1 mg$98In Stock
2 mg$153In Stock
5 mg$218In Stock
10 mg$328In Stock
25 mg$553In Stock
50 mg$796In Stock
100 mg$1,090In Stock
1 mL x 10 mM (in DMSO)$228In Stock
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Purity:99.61%
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Product Introduction

Bioactivity
Description
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
Targets&IC50
5-HT2A receptor:5.2 (pKi), 5-HT2C receptor:6.9 (pKi) , 5-HT2B receptor:7.5 (pKi)
Chemical Properties
Molecular Weight266.3
FormulaC15H14N4O
Cas No.143797-63-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 53 mg/mL (199.02 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7552 mL18.7758 mL37.5516 mL187.7582 mL
5 mM0.7510 mL3.7552 mL7.5103 mL37.5516 mL
10 mM0.3755 mL1.8776 mL3.7552 mL18.7758 mL
20 mM0.1878 mL0.9388 mL1.8776 mL9.3879 mL
50 mM0.0751 mL0.3755 mL0.7510 mL3.7552 mL
100 mM0.0376 mL0.1878 mL0.3755 mL1.8776 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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