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Solifenacin succinate

Catalog No. T0111   CAS 242478-38-2
Synonyms: YM905

Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.

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Solifenacin succinate Chemical Structure
Solifenacin succinate, CAS 242478-38-2
Pack Size Availability Price/USD Quantity
25 mg In stock $ 33.00
50 mg In stock $ 47.00
100 mg In stock $ 89.00
200 mg In stock $ 121.00
500 mg In stock $ 196.00
1 g In stock $ 289.00
1 mL * 10 mM (in DMSO) In stock $ 29.00
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Purity: 99.73%
Purity: 99.3%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.
In vivo Solifenacin succinate is a novel muscarinic antagonist indicated for the treatment of overactive bladder syndrome. When co-administered with oxybutynin, Solifenacin effectively inhibits the mobilization of intracellular calcium mediated by muscarinic M3 receptors in isolated bladder smooth muscle cells of guinea pigs and submandibular gland cells of mice.
Synonyms YM905
Molecular Weight 480.56
Formula C23H26N2O2·C4H6O4
CAS No. 242478-38-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (52.02 mM)

TargetMolReferences and Literature

1. Ikeda K, et al. Naunyn Schmiedebergs Arch Pharmacol, 2002, 366(2), 97-103. 2. Cardozo L, et al. J Urol, 2004, 172(5 Pt 1), 1919-1924.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Neurodegenerative Disease Compound Library Neuronal Signaling Compound Library Anti-Parkinson's Disease Compound Library Bioactive Compound Library Drug-induced Liver Injury (DILI) Compound Library Drug Repurposing Compound Library Bioactive Compounds Library Max GPCR Compound Library Orally Active Compound Library Neurotransmitter Receptor Compound Library

Related Products

Related compounds with same targets
Propantheline bromide Vesamicol hydrochloride (Rac)-ABT-202 dihydrochloride Pimethixene maleate Pozanicline Nicardipine hydrochloride Adiphenine hydrochloride Fesoterodine

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Keywords

Solifenacin succinate 242478-38-2 Neuroscience AChR inhibit YM905 YM-905 Muscarinic acetylcholine receptor YM 905 Inhibitor Solifenacin Solifenacin Succinate mAChR inhibitor

 

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