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Tianeptine
Catalog No. T8140Cas No. 72797-41-2
Alias TPI-1062, Tianeptine sodium, S-1574, JNJ-39823277
Tianeptine (Tianeptine sodium) is a selective 5-HT uptake facilitator in vitro and in vivo.
Tianeptine
Catalog No. T8140Alias TPI-1062, Tianeptine sodium, S-1574, JNJ-39823277Cas No. 72797-41-2
Tianeptine (Tianeptine sodium) is a selective 5-HT uptake facilitator in vitro and in vivo.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $31 | In Stock | |
| 25 mg | $48 | In Stock | |
| 50 mg | $73 | In Stock | |
| 100 mg | $107 | In Stock | |
| 500 mg | $265 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock |
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CitedSelect Batch
Purity:≥95%
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | Tianeptine (Tianeptine sodium) is a selective 5-HT uptake facilitator in vitro and in vivo. |
| In vivo | tianeptine pretreatment upon corticosterone release and body weight loss following L-5-hydroxytryptophan (5-HTP) administration in conscious rats.?Administration of 5-HTP (20 mg/kg i.v.) increased plasma corticosterone levels to a similar extent in rats pretreated either with saline or tianeptine (10 mg/kg i.p., 60 min beforehand).?Besides, prior administration of benserazide (50 mg/kg i.p., 30 min beforehand), an inhibitor of peripheral aromatic L-amino acid decarboxylase, prevented 5-HTP-induced corticosterone release in both saline- and tianeptine-pretreated rats.?However, combined administration of benserazide and 5-HTP decreased overnight body weight in saline-, but not in tianeptine-pretreated rats.?These results suggest that tianeptine preferentially activates 5-HT reuptake in central serotonergic neurones. |
| Alias | TPI-1062, Tianeptine sodium, S-1574, JNJ-39823277 |
| Molecular Weight | 436.95 |
| Formula | C21H25ClN2O4S |
| Cas No. | 72797-41-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (125.87 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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