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Trifluoperazine

Catalog No. T8389   CAS 117-89-5
Synonyms: trifluoroperazine

Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.

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Trifluoperazine Chemical Structure
Trifluoperazine, CAS 117-89-5
Pack Size Availability Price/USD Quantity
1 mg In stock $ 41.00
2 mg In stock $ 57.00
5 mg In stock $ 82.00
10 mg In stock $ 123.00
25 mg In stock $ 225.00
50 mg In stock $ 352.00
100 mg In stock $ 529.00
500 mg In stock $ 1,180.00
1 mL * 10 mM (in DMSO) In stock $ 108.00
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Purity: 99.03%
Purity: 98.3%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
Targets&IC50 D2:1.2 nM
Synonyms trifluoroperazine
Molecular Weight 407.5
Formula C21H24F3N3S
CAS No. 117-89-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (24.54 mM)

TargetMolReferences and Literature

1. Magdolna, Tardy, Markus,et al. Trifluoperazine versus low-potency first-generation antipsychotic drugs for schizophrenia[J]. Cochrane Database of Systematic Reviews, 2014. 2. Koch K , Mansi K , Haynes E , et al. Trifluoperazine versus placebo for schizophrenia[J]. Cochrane Database of Systematic Reviews, 2014, 1(1):CD010226. 3. Lu J, Hou Y, Ge S, et al. Screened antipsychotic drugs inhibit SARS-CoV-2 binding with ACE2 in vitro[J]. Life Sciences . 2020: 118889.

TargetMolCitations

1. Lu J, Hou Y, Ge S, et al. Screened antipsychotic drugs inhibit SARS-CoV-2 binding with ACE2 in vitro. Life Sciences. 2020: 118889.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Anti-Cancer Drug Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library Human Metabolite Library Anti-Cardiovascular Disease Compound Library Clinical Compound Library ReFRAME Related Library Anti-Alzheimer's Disease Compound Library

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Keywords

Trifluoperazine 117-89-5 Autophagy GPCR/G Protein Membrane transporter/Ion channel Microbiology/Virology Neuroscience Adrenergic Receptor P-gp CaMK Influenza Virus Dopamine Receptor Inhibitor morphogenesis Calmodulin-dependent protein kinases antipsychotic ABCB1 P-glycoprotein Multidrug resistance protein 1 inhibit MDR1 CD243 Pgp Cluster of differentiation 243 anticancer NUPR1 schizophrenia Beta Receptor trifluoroperazine Calmodulin-dependent kinases inhibitor

 

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