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Dicyclomine hydrochloride

Dicyclomine hydrochloride
Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.
Catalog No. T1460Cas No. 67-92-5
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Purity:99.91%
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Dicyclomine hydrochloride

Catalog No. T1460Cas No. 67-92-5

Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.
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Pack SizePriceAvailabilityQuantity
500 mg$42In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Product Introduction

Bioactivity
Description
Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.
Targets&IC50
M1 mAChR (brush-border membrane):5.1 nM (Ki)
Chemical Properties
Molecular Weight345.95
FormulaC19H36ClNO2
Cas No.67-92-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 199.5 mM
DMSO: 60 mg/mL (173.44 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.8906 mL14.4530 mL28.9059 mL144.5296 mL
5 mM0.5781 mL2.8906 mL5.7812 mL28.9059 mL
10 mM0.2891 mL1.4453 mL2.8906 mL14.4530 mL
20 mM0.1445 mL0.7226 mL1.4453 mL7.2265 mL
50 mM0.0578 mL0.2891 mL0.5781 mL2.8906 mL
100 mM0.0289 mL0.1445 mL0.2891 mL1.4453 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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