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Rotigotine Hydrochloride
🥰Excellent
Catalog No. T21446Cas No. 125572-93-2
Alias Rotigotine HCl, Rotigotine (Hydrochloride), N-0924, N-0923, N 0923
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinpirole, the gold standard D2 agonist.
Rotigotine Hydrochloride
🥰Excellent
Purity: 99.66%
Catalog No. T21446Alias Rotigotine HCl, Rotigotine (Hydrochloride), N-0924, N-0923, N 0923Cas No. 125572-93-2
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinpirole, the gold standard D2 agonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $37 | In Stock | |
| 10 mg | $54 | In Stock | |
| 25 mg | $88 | In Stock | |
| 50 mg | $118 | In Stock | |
| 100 mg | $162 | In Stock | |
| 200 mg | $239 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $40 | In Stock |
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5-HT ReceptorAChRAdrenergic ReceptorHistamine ReceptorNorepinephrineSerotonin TransporterSigma receptorSodium ChannelTrk receptor
- $45
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Purity:99.66%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinpirole, the gold standard D2 agonist. |
| Targets&IC50 | α1B:273 nM (Ki), 5-HT7 receptor:86 nM (Ki), α2B:27 nM (Ki), 5-HT1A receptor:30 nM (Ki), D3 receptor:0.71 nM (Ki), α2A:338 nM (Ki), D4 receptor:4-15 nM (Ki), D1 receptor:83 nM (Ki), α1A:176 nM (Ki), D2 receptor:4-15 nM (Ki), D5 receptor:4-15 nM (Ki) |
| Alias | Rotigotine HCl, Rotigotine (Hydrochloride), N-0924, N-0923, N 0923 |
| Molecular Weight | 351.93 |
| Formula | C19H26ClNOS |
| Cas No. | 125572-93-2 |
| Smiles | Cl.CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1 |
| Relative Density. | 1.2 g/cm3 at 20℃ |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 70 mg/mL (198.9 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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