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Vecuronium bromide
🥰Excellent
Catalog No. T1594Cas No. 50700-72-6
Alias ORG NC 45
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting, mono-quaternary steroid that functions as a non-depolarizing neuromuscular blocking agent with muscle relaxant properties.
Vecuronium bromide
🥰Excellent
Purity: 99.92%
Catalog No. T1594Alias ORG NC 45Cas No. 50700-72-6
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting, mono-quaternary steroid that functions as a non-depolarizing neuromuscular blocking agent with muscle relaxant properties.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | 28 € | In Stock | |
| 25 mg | 42 € | In Stock | |
| 50 mg | 64 € | In Stock | |
| 100 mg | 93 € | In Stock | |
| 500 mg | 206 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 45 € | In Stock |
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Purity:99.92%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting, mono-quaternary steroid that functions as a non-depolarizing neuromuscular blocking agent with muscle relaxant properties. |
| In vitro | Vecuronium inhibits both forms of the muscle-type acetylcholine receptor (IC50: 1-2 nM). Vecuronium combined with methylprednisolone shows additive effects on both receptor forms.[1] Vecuronium interferes with nicotinic processes in the carotid body and inhibits the chemoreceptor neural response to hypoxia. Vecuronium significantly attenuates the increase in CSNA (DeltaCSNA) in response to hypoxia in the carotid body.[2] |
| In vivo | Vecuronium has a higher biliary clearance than pancuronium in the rats.[3] |
| Alias | ORG NC 45 |
| Molecular Weight | 637.73 |
| Formula | C34H57BrN2O4 |
| Cas No. | 50700-72-6 |
| Smiles | [Br-].CC(=O)OC1C(CC2C3CCC4CC(OC(C)=O)C(CC4(C)C3CCC12C)N1CCCCC1)[N+]1(C)CCCCC1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 4 mg/mL (6.27 mM) Ethanol: 93 mg/mL (145.8 mM) DMSO: 93 mg/mL (145.8 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/Ethanol/DMSO
Ethanol/DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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