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Duloxetine hydrochloride
🥰Excellent
Catalog No. T1471Cas No. 136434-34-9
Alias LY-248686 hydrochloride, LY-248686 HCl, Duloxetine HCl, (S)-Duloxetine hydrochloride
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for serotonin and noradrenaline (SNRI). It is an antidepressant agent and anxiolytic, also used for treating pain in patients with diabetes mellitus and fibromyalgia.
Duloxetine hydrochloride
🥰Excellent
Purity: 100%
Catalog No. T1471Alias LY-248686 hydrochloride, LY-248686 HCl, Duloxetine HCl, (S)-Duloxetine hydrochlorideCas No. 136434-34-9
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for serotonin and noradrenaline (SNRI). It is an antidepressant agent and anxiolytic, also used for treating pain in patients with diabetes mellitus and fibromyalgia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $48 | In Stock | |
| 50 mg | $78 | In Stock | |
| 100 mg | $108 | In Stock | |
| 200 mg | $135 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for serotonin and noradrenaline (SNRI). It is an antidepressant agent and anxiolytic, also used for treating pain in patients with diabetes mellitus and fibromyalgia. |
| Targets&IC50 | SNRI:4.6 nM(Ki) |
| Alias | LY-248686 hydrochloride, LY-248686 HCl, Duloxetine HCl, (S)-Duloxetine hydrochloride |
| Molecular Weight | 333.88 |
| Formula | C18H20ClNOS |
| Cas No. | 136434-34-9 |
| Smiles | s1cccc1[C@@H](Oc1cccc2c1cccc2)CCNC.Cl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (119.8 mM)  Ethanol: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords
SLC6A4Sert (Sodium-dependent)SERTSerotoninTransporterSerotonin TransporterpainosteoarthiritisNoradrenaline transporter (Sodium-dependent)musculoskeletalLY-248686 HydrochlorideLY248686 HydrochlorideLY-248686LY248686LY 248686 HydrochlorideLY 248686InhibitorinhibitgeneralizedDuloxetine hydrochlorideDuloxetine HydrochlorideDuloxetineDopamineReceptorDopamine ReceptordisorderdepressiveDA transporteranxiety5-HTT5HTReceptor5HT Receptor(S)-Duloxetine
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