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Sulfoxaflor

Sulfoxaflor
Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide that acts on the insect central nervous system. Sulfoxaflor was found to have some effects on peripheral blood lymphocytes and is used to control sap-feeding insects such as brown planthopper, whitefly, peach aphid, and cotton aphid.
Catalog No. T19940Cas No. 946578-00-3
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Purity:99.87%
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Sulfoxaflor

Purity: 99.87%
Catalog No. T19940Alias XDE 208, GF 2372, GF 2032Cas No. 946578-00-3

Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide that acts on the insect central nervous system. Sulfoxaflor was found to have some effects on peripheral blood lymphocytes and is used to control sap-feeding insects such as brown planthopper, whitefly, peach aphid, and cotton aphid.
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Pack SizePriceAvailabilityQuantity
1 mg$113In Stock
5 mg$322In Stock
10 mg$479In Stock
25 mg$768In Stock
50 mg$1,050In Stock
100 mg$1,390In Stock
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Product Introduction

Bioactivity
Description
Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide that acts on the insect central nervous system. Sulfoxaflor was found to have some effects on peripheral blood lymphocytes and is used to control sap-feeding insects such as brown planthopper, whitefly, peach aphid, and cotton aphid.
In vitro
METHODS: Blood lymphocytes were treated with Sulfoxaflor (GF 2032) (10 µg/mL, 20 µg/mL, 40 µg/mL), and single cell gel electrophoresis (comet electrophoresis), cytokinesis block micronucleus assay (MN assay), flow cytometry, and catalase (CAT) enzyme activity measurement were used to determine genotoxicity, apoptotic effects, and oxidative damage potential, respectively.
RESULTS CPBI values ​​and the number of viable cells decreased; the number of late apoptotic and necrotic cells, micronucleus frequency, and comet assay parameters (GDI and DCP) increased; an increase in CAT enzyme levels was observed at 10 and 20 µg/mL concentrations, and CAT enzyme activity was inhibited at 40 µg/mL. [3]
In vivo
METHODS: Sulfoxaflor (GF 2032) (25, 100, and 500 mg/kg, gavage, 4 weeks) was administered to rats and the relative testicular mass, testosterone, FSH, LH, MDA, and GPx levels, sperm motility, sperm morphology, sperm DNA damage, and histopathological changes in the testis, epididymis, and seminal vesicle were examined.
RESULTS Sulfoxaflor exposure resulted in an increase in FSH, LH, MDA, and GPx levels in sperm, as well as the percentage of dead and abnormal sperm and DNA damage in rat sperm. [2]
AliasXDE 208, GF 2372, GF 2032
Chemical Properties
Molecular Weight277.27
FormulaC10H10F3N3OS
Cas No.946578-00-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (199.09 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6066 mL18.0330 mL36.0659 mL180.3296 mL
5 mM0.7213 mL3.6066 mL7.2132 mL36.0659 mL
10 mM0.3607 mL1.8033 mL3.6066 mL18.0330 mL
20 mM0.1803 mL0.9016 mL1.8033 mL9.0165 mL
50 mM0.0721 mL0.3607 mL0.7213 mL3.6066 mL
100 mM0.0361 mL0.1803 mL0.3607 mL1.8033 mL

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