Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Verapamil hydrochloride

Verapamil hydrochloride
Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.
Catalog No. T1010Cas No. 152-11-4
Select Batch
Purity:99.98%
Contact us for more batch information

Resource Download

Verapamil hydrochloride

Purity: 99.98%
Catalog No. T1010Alias Verapamil HCl, Manidon, Calcan hydrochloride, (±)-Verapamil hydrochloridCas No. 152-11-4

Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
500 mg$41In Stock
1 g$48In Stock
1 mL x 10 mM (in DMSO)$45In Stock
Bulk & Custom
Add to Cart

Related Compound Libraries of "Verapamil hydrochloride"

Product Introduction

Bioactivity
Description
Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.
In vitro
Verapamil exhibits antiarrhythmic properties, reduces myocardial oxygen consumption in rats, and preserves Cx43 protein.
In vivo
Verapamil and Diltiazem essentially inhibit the hydrolase activity of recombinant CES2, with inhibition constants (Ki) of 0.25 ± 0.02 μM and 3.84 ± 0.99 μM, respectively.
Cell Research
Verapamil is dissolved in DMSO and stored, and then diluted with appropriate media before use[1]. Cells (1×105) are treated with 10 nM Bortezomib and/or 70 μM Verapamil for 16 hours and incubated for another 4 hours with Alamar-Blue. Activity of the mitochondrial dehydrogenase results in conversion of the coloring, which is followed by measurement of the absorption using a spectrophotometer[1].
AliasVerapamil HCl, Manidon, Calcan hydrochloride, (±)-Verapamil hydrochlorid
Chemical Properties
Molecular Weight491.06
FormulaC27H39ClN2O4
Cas No.152-11-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (101.82 mM)
H2O: 24.6 mg/mL (50 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.0364 mL10.1821 mL20.3641 mL101.8206 mL
5 mM0.4073 mL2.0364 mL4.0728 mL20.3641 mL
10 mM0.2036 mL1.0182 mL2.0364 mL10.1821 mL
20 mM0.1018 mL0.5091 mL1.0182 mL5.0910 mL
50 mM0.0407 mL0.2036 mL0.4073 mL2.0364 mL
DMSO
1mg5mg10mg50mg
100 mM0.0204 mL0.1018 mL0.2036 mL1.0182 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Verapamil hydrochloride | purchase Verapamil hydrochloride | Verapamil hydrochloride cost | order Verapamil hydrochloride | Verapamil hydrochloride chemical structure | Verapamil hydrochloride in vivo | Verapamil hydrochloride in vitro | Verapamil hydrochloride formula | Verapamil hydrochloride molecular weight