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Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $36 | Backorder | |
10 mg | $60 | Backorder | |
25 mg | $83 | Backorder | |
50 mg | $106 | Backorder | |
100 mg | $179 | Backorder | |
200 mg | $268 | Backorder | |
1 mL x 10 mM (in DMSO) | $47 | Backorder |
Description | Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. |
In vivo | Six female Persian onagers (Equus hemionus onager) were treated with fluphenazine decanoate (FD;?0.1?mg/kg IM) or saline control in a random crossover design study.?Urinary cortisol, progesterone, estrogen metabolites and behavior were monitored, and follicular dynamics were examined using ultrasonography until ovulation.?Onagers demonstrated significantly lower cortisol concentrations (P?=?0.03) when treated with FD (6.61?±?3.26?ng/mg creatinine) compared to saline (9.73?±?3.19?ng/mg creatinine).?Overall, there were no differences in peak estrogen (P?=?0.51) or progesterone (P?=?0.38) concentrations between the two groups, and all animals ovulated within the expected time frame following FD treatment.?However, some onagers exhibited only minor reductions in cortisol secretion and one treated female demonstrated a suppressed luteal progesterone peak, indicating a possible reproductive cost to FD administration[1]. |
Molecular Weight | 591.77 |
Formula | C32H44F3N3O2S |
Cas No. | 5002-47-1 |
Smiles | CCCCCCCCCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |
Relative Density. | 1.149 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 125 mg/mL (211.23 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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