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Metoclopramide hydrochloride hydrate

Metoclopramide hydrochloride hydrate
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Purity:100%
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Metoclopramide hydrochloride hydrate

Catalog No. T8385Cas No. 54143-57-6
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic
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Pack SizePriceAvailabilityQuantity
100 mg$74In Stock
200 mg$98In Stock
500 mg$148In Stock
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Product Introduction

Bioactivity
Description
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic
Targets&IC50
5-HT3 receptor:308 nM (IC50), D2 receptor:483 nM (IC50)
AliasMetoclopramide monohydrochloride monohydrate
Chemical Properties
Molecular Weight354.27
FormulaC14H25Cl2N3O3
Cas No.54143-57-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (141.14 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8227 mL14.1135 mL28.2271 mL141.1353 mL
5 mM0.5645 mL2.8227 mL5.6454 mL28.2271 mL
10 mM0.2823 mL1.4114 mL2.8227 mL14.1135 mL
20 mM0.1411 mL0.7057 mL1.4114 mL7.0568 mL
50 mM0.0565 mL0.2823 mL0.5645 mL2.8227 mL
100 mM0.0282 mL0.1411 mL0.2823 mL1.4114 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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