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Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $48 | In Stock | |
25 mg | $64 | In Stock | |
50 mg | $81 | In Stock | |
100 mg | $108 | In Stock | |
200 mg | $162 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities. |
Targets&IC50 | 5-HT3 receptor:70.1 ± 0.9 nM |
In vivo | Tropisetron (1 mg/kg i.p.) significantly improves the deficient inhibitory processing of the P20-N40 auditory evoked potential in DBA/2 mice. [5] |
Alias | Tropisetron HCl, SDZ-ICS 930, ICS 205-930 |
Molecular Weight | 320.82 |
Formula | C17H21ClN2O2 |
Cas No. | 105826-92-4 |
Smiles | Cl.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 6.25 mg/mL (19.48 mM), Sonication is recommended. H2O: 50 mg/mL (155.86 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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