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Tropisetron hydrochloride

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Catalog No. T1173Cas No. 105826-92-4
Alias Tropisetron HCl, SDZ-ICS 930, ICS 205-930

Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.

Tropisetron hydrochloride

Tropisetron hydrochloride

🥰Excellent
Purity: 99.83%
Catalog No. T1173Alias Tropisetron HCl, SDZ-ICS 930, ICS 205-930Cas No. 105826-92-4
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.
Pack SizePriceAvailabilityQuantity
10 mg$48In Stock
25 mg$64In Stock
50 mg$81In Stock
100 mg$108In Stock
200 mg$162In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.83%
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Product Introduction

Bioactivity
Description
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.
Targets&IC50
5-HT3 receptor:70.1 ± 0.9 nM
In vivo
Tropisetron (1 mg/kg i.p.) significantly improves the deficient inhibitory processing of the P20-N40 auditory evoked potential in DBA/2 mice. [5]
AliasTropisetron HCl, SDZ-ICS 930, ICS 205-930
Chemical Properties
Molecular Weight320.82
FormulaC17H21ClN2O2
Cas No.105826-92-4
SmilesCl.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 6.25 mg/mL (19.48 mM), Sonication is recommended.
H2O: 50 mg/mL (155.86 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM3.1170 mL15.5851 mL31.1701 mL155.8506 mL
5 mM0.6234 mL3.1170 mL6.2340 mL31.1701 mL
10 mM0.3117 mL1.5585 mL3.1170 mL15.5851 mL
H2O
1mg5mg10mg50mg
20 mM0.1559 mL0.7793 mL1.5585 mL7.7925 mL
50 mM0.0623 mL0.3117 mL0.6234 mL3.1170 mL
100 mM0.0312 mL0.1559 mL0.3117 mL1.5585 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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