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Thioridazine hydrochloride

🥰Excellent
Catalog No. T0365Cas No. 130-61-0
Alias Mellaril, Aldazine

Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.

Thioridazine hydrochloride

Thioridazine hydrochloride

🥰Excellent
Purity: 99.55%
Catalog No. T0365Alias Mellaril, AldazineCas No. 130-61-0
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
Pack SizePriceAvailabilityQuantity
50 mg$36In Stock
100 mg$48In Stock
200 mg$59In Stock
500 mg$81In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Questions
QWhat's the meaning of "< 1 mg/mL refers to the slightly soluble or insoluble"?
AIt means that if the solubility is less than 1 mg/mL
QWhat is the calculation method for preparing a solution?
AThe calculation method is as follows: (1) c=n/v=m/M/v Concentration=amount of substance/volume=mass/molar mass/volume (2) The solution preparation table is presented in the the product details page on our website. You can add the volume of solvent as referenced.
QCan inhibitors be used for animal experiments?
AYes, our inhibitors can be used for animal/in vivo experiments. However, some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.
QWhat should I do if the products in powder form adhere to the vial tightly?
AIt's recommended to centrifuge it at 3000 rpm for a few minutes.
QHow should inhibitors be dissolved for cell experiments?
AInhibitors are typically dissolved in DMSO to prepare a concentrated stock solution. Please store at -80°C and aliquot the product to avoid repeated freeze-thaw cycles. For short-term use within one week, aliquots can be stored at 4°C. When diluting in experiments, PBS, physiological saline, culture medium, and water are commonly used. (Note: In cell experiments, the final concentration of DMSO should not exceed 0.1%. If it exceeds 0.1%, it's necessary to conduct a negative control experiment during preliminary test to assess any potential effects of the solvent on cells.)
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Purity:99.55%
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Product Introduction

Bioactivity
Description
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
AliasMellaril, Aldazine
Chemical Properties
Molecular Weight407.04
FormulaC21H27ClN2S2
Cas No.130-61-0
SmilesCl.CSc1cc2c(Sc3ccccc3N2CCC2CCCCN2C)cc1
Relative Density.1.1227 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (135.12 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4568 mL12.2838 mL24.5676 mL122.8381 mL
5 mM0.4914 mL2.4568 mL4.9135 mL24.5676 mL
10 mM0.2457 mL1.2284 mL2.4568 mL12.2838 mL
20 mM0.1228 mL0.6142 mL1.2284 mL6.1419 mL
50 mM0.0491 mL0.2457 mL0.4914 mL2.4568 mL
100 mM0.0246 mL0.1228 mL0.2457 mL1.2284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

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References

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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