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r1507

" in TargetMol Product Catalog

Inhibitors & Agonists
1
Inhibitory Antibodies
1

Teprotumumab

T767271036734-93-6

Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-associated eye diseases.

TSH Receptor IGF-1R

$198

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