block lipid transport1

Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).

Lipid-lowering agent-1 is a potent lipid-lowering compound that significantly inhibits the pharmacological effects of low-density lipoprotein cholesterol (LDLC) and promotes high-density lipoprotein cholesterol (HDLC) production. In rats on a high-fat diet, it substantially reduces fat.

Ionizable Lipid-1 (compound II-10), with a pKa of 6.16, is an ionizable lipid capable of forming lipid nanoparticles (LNP) with a bilayer structure [1].

LNP Lipid-1 (Method B), a lipid compound, plays a crucial role in the formulation of lipid nanoparticles compositions and exhibits potential for transporting biologically active substances, including small molecule agents, proteins, and nucleic acids [1] [2].

mRNA-Encapsulating Lipid Excipient 1 (Compound 2), a thiocarbamate-based ionizable lipid, serves as an excipient in the formulation of mRNA-encapsulating lipid nanoparticles [1].

BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.