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Results for "
jh viii 157 02
" in TargetMol Product Catalog- Inhibitors & Agonists4
- PROTAC Products2
JH-VIII-157-02
T156121639422-97-1
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.
- $118
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JH-XII-03-02
T793512415900-86-4
JH-XII-03-02 is a potent, selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD) research [1].
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JH-VIII-49
T242002209084-73-9
JH-VIII-49 is an effective and selective inhibitor of CDK8.
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JH-XI-10-02
T137432209085-22-1
JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
- $1,440
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