Beta Amyloid

Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection.

Cat. No.	Product name	CAS No.	Purity
TP2419	V-9-M Cholecystokinin nonapeptide	99291-20-0	98.75%
TP2419	V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal pepti...
TMS1461	Qingyangshengenin B	106758-54-7	98.56%
TMS1461	Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases...
T6562	Latrepirdine dihydrochloride	97657-92-6	98.45%
T6562	Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors,...
T5810	TABERSONINE HYDROCHLORIDE	29479-00-3	98.17%
T5810	TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.
T14283	Amyloid P-IN-1	1819986-22-5	98.03%
T14283	amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and t...
T14199	ALZ-801	1034190-08-3	98%
T14199	ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer'...
T7527	Frentizole	26130-02-9	98%
T7527	Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction
T8012	Scyllo-Inositol	488-59-5	98%
T8012	Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for Alzheim...
T21825	TAE-1	1414469-59-2	98%
T21825	TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
T2262	Itanapraced	749269-83-8	98%
T2262	Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).
T7490	ARN2966	102212-26-0	98%
T7490	ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.
T14284	β-Amyloid (25-35)	131602-53-4	97.91%
T14284	β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
T7566L1	GRGDSPK acetate	144027-77-0	97.9%
T7566L1	GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.
T6274	RO4929097	847925-91-1	97.68%
T6274	RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
TN6919	Methyl tridecanoate	1731-88-0	97.63%
TN6919	Methyl tridecanoate is a natural product.
T19892	BSBM7	6968-11-2	97.27%
T19892	BSBM7 is an inhibitor of Aβ aggregation and neuronal toxicity.
T22417	Rutin hydrate	190836-14-7	97.23%
T22417	Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.
TP1786L	Amyloid β-Protein 10-20 acetate	TP1786L	97.23%
TP1786L	Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research of neuro...
T1686	Hematoxylin	517-28-2	97.09%
T1686	Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in...
T2507	Azeliragon	603148-36-3	96.7%
T2507	Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-moderat...