Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.

Cat. No.	Product name	CAS No.	Purity
T4571	Balsalazide	80573-04-2	98%
T4571	Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
T2S0843	Negletein	29550-13-8	99.92%
T2S0843	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotecta...
T4403	AX-024 hydrochloride	1704801-24-0	99.9%
T4403	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
T8280	Deacetylasperulosidic Acid	14259-55-3	99.88%
T8280	Deacetylasperulosidic Acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also pr...
T4450	GIBH-130	1252608-59-5	99.86%
T4450	GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
T3829	Ginsenoside F3	62025-50-7	99.84%
T3829	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
T2932	Ginsenoside Rh1	63223-86-9	99.77%
T2932	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T6S1538	Neochlorogenic acid	906-33-2	99.73%
T6S1538	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T26326	VU0285655-1	1158347-73-9	99.73%
T26326	VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhib...
TQ0181	Resatorvid	243984-11-4	99.73%
TQ0181	Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid binds directly to Cys747 and prevents TLR4 from binding to TIRAP, thereb...
T9913	Ustekinumab	815610-63-0	99.70%
T9913	Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
T3533	Apilimod mesylate	870087-36-8	99.7%
T3533	Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.
T9157	GP130 receptor agonist-1	339303-87-6	99.7%
T9157	GP130 receptor agonist-1 (N-(4-Fluorophenyl)-4-phenyl-2-thiazolami) is a potent, brain-penetrant and orally active GP130 receptor agonist.
T3133	YM-90709	163769-88-8	99.67%
T3133	YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
T2S0342	Armillarisin A	53696-74-5	99.67%
T2S0342	Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
T2720	Ginsenoside Rc	11021-14-0	99.66%
T2720	Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
T2601	Vidofludimus	717824-30-1	99.58%
T2601	Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T2758	Madecassic acid	18449-41-7	99.55%
T2758	Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
T10389	Aspartyl-alanyl-diketopiperazine	110954-19-3	99.54%
T10389	Aspartyl-alanyl-diketopiperazine (DA-DKP) is a known immunomodulatory molecule from the N terminus of human albumin.
T9911	Tocilizumab	375823-41-9	99.50%
T9911	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor