datasheet/T7575L1

L-Threonine derivative-1 is acetylsalicylic acid-L-threonine ester with potential analgesic activity.

(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl dihydrogen diphosphate,tetrabutylammonium(1:1.5) is a common precursor of taxadiene such as Paclitaxel.

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.

Geranylgeranyl pyrophosphate tetrabutylammonium(1：2) is one of the endogenous cholesterol and intermediates produced by the mevalerate pathway. Geranylgeranyl pyrophosphate tetrabutylammonium(1：2) is the common precursor of diterpenoids, for example, Paclitaxel. It can be used for cancer research.

(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside is a natural product isolated from the bulbs of Lilium brownii var. viridulum.

L-97-1 is an antagonist of the adenosine A1 receptor.

1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs[1].

1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines.

1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N6-benzoyladenine is a useful organic compound for research related to life sciences. The catalog number is TNU1629 and the CAS number is 325683-88-3.

Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and invasive effects, it effectively impacts pancreatic cancer BxPC-3 and PANC-1 cells.

2,5-Dioxopyrrolidin-1-yl ((benzyloxy)carbonyl)-L-alaninate is a useful organic compound for research related to life sciences. The catalog number is T65500 and the CAS number is 3401-36-3.

1-(alpha-L-Threofuranosyl)thymine is a Nucleoside Derivative - L-nucleoside.

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) is a compound extracted from the leaves of Ginkgo biloba. Quercetin 3-o - -(6 '-p-coumaryl) glucopyranose (1->2) -α-L-rhamnoside has antioxidant properties.

N-[(S)-1-Carbethoxy-1-butyl]-L-alanine is a useful organic compound for research related to life sciences. The catalog number is T65104 and the CAS number is 82834-12-6.

C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).

1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine is a useful organic compound for research related to life sciences. The catalog number is TNU1627 and the CAS number is 325683-90-7.

1-O-(4,4'-Dimethoxytrityl)-3-O-succinyl-l,3-propanediol is a Fine Chemical.

L-Lysine, sulfite (2:1) is a drug/ therapeutic agent.

L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4.

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside shows antioxidant activity.

L-Glucose-1-14C is the L-isomer of glucose. It also is the enantiomer of the more common D-glucose.

Hederagenin 28-O-{β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester}3-O-{α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl} is a saponin known for its antitumor and anti-inflammatory properties [1].

Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis.

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product, and has good pharmacological effects on the cardiovascular system.

Nε-(1-Carboxymethyl)-L-lysine (CML), an advanced glycation end product (AGE), is formed through the oxidative modification of glycated proteins under conditions of oxidative stress.1,2,3 Its levels escalate with age, diabetes, cancer, vascular diseases, and various pathologies associated with oxidative stress.1,4,5 CML interacts with the membrane-bound receptor for AGEs (RAGE), initiating signaling via MAPKs and NF-κB pathways. Conversely, a truncated version of RAGE generates a soluble protein that sequesters CML, thereby diminishing this signaling.6,7

Nucleoside Derivatives - L-Nucleosides; Protected nucleosides w/NH2/OH open

1-O-Acetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose is a Carbohydrate Derivative.

L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.

Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product obtained through NADPH oxidase activation and Lyso-PS signal transduction. Oleoyl-2-hydroxy-sn-glycero-3phospho-L-serine sodium is able to utilize macrophage G2A function to enhance the existing receptor/ligand system and thereby resolve neutrophil inflammation.

somatostatin sst2 receptor agonist

1,4-Anhydro-2-de oxy-3-O-(t-butyldiphenylsilyl-D-erythro-pent-1-enitol is a useful organic compound for research related to life sciences. The catalog number is TNU1443 and the CAS number is 130277-32-6.

Nε-(1-Carboxyethyl)-L-lysine (CEL), a known advanced glycation end product (AGE), forms through the interaction of methyl glyoxal and lysine residues within proteins. Unlike its free form, protein-bound CEL can attach to the receptor for AGEs (RAGE). Its concentrations are notably higher in the lenses of diabetic cataract patients and are reduced in rat heart mitochondria following sustained caloric restriction. Furthermore, at 1 mM, CEL impedes glutamate uptake and the release of S100B in rat hippocampal slices, an effect that occurs independently of RAGE.

1-(alpha-L-Threofuranosyl)cytosine is a Nucleoside Derivative - L-nucleoside.

Fmoc-1-methyl-L-histidine is a useful organic compound for research related to life sciences. The catalog number is T66680 and the CAS number is 202920-22-7.

C18 L-erythro Ceramide (d18:1/18:0) significantly reduced extracellular Aβ levels and can be used to study Alzheimer's disease.

C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.

Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside] is a natural product

Swertianin 2-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside is a natural product for research related to life sciences. The catalog number is TN5919 and the CAS number is 136832-00-3.

1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1628 and the CAS number is 325683-91-8.

C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.

S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensive animal models.

Urea, 1-(L-glucosyl)-2-thio- is a bioactive chemical.

Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside, also known as compound 8, is a flavonoid glycoside isolated from the leaf extract of the black locust (Leguminosae)[1].

Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside (Compound 12), a cardiac glycoside extracted from Thevetia peruviana seeds, exhibits cytotoxic effects on SW1990 and MGC-803 cells with IC50 values of 9.52 and 7.70 μM, respectively [1].

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol, a cuminol glycoside, can be isolated from Rhodiola rosea^[1].

RNase L-IN-1 (compound 17a) functions as an inhibitor of RNase L (Ribonuclease L), an enzyme responsible for RNA degradation to inhibit viral replication, and plays a crucial role in mediating innate immune responses and inflammation [1].

Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside (Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside) is main antioxidant of Shuxuening, an herbal medicines injection.

1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate, a lipid, plays a crucial role in the synthesis of phospholipid vesicles and enhances the encapsulation efficiency of proteins [1].

1-Methyl L-Glutamate is a useful organic compound for research related to life sciences. The catalog number is T66113 and the CAS number is 6384-08-3.

1,4-Anhydro-2-deoxy-3,5-bis-O-(t-butyl diphenylsilyl-D-erythro-pent-1-enitol is a useful organic compound for research related to life sciences. The catalog number is TNU1642 and the CAS number is 105930-84-5.