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Results for "
ch 150
" in TargetMol Product Catalog- Inhibitors & Agonists2
Tubulin/HDAC-IN-1
T615242413587-26-3
Tubulin HDAC-IN-1 is a dual inhibitor of tubulin and HDAC8, interacting with tubulin via CH π interactions and with HDAC8 through hydrogen bonds. It effectively inhibits tubulin polymerization and selectively targets HDAC8 with an IC50 of 150 nM. Additionally, Tubulin HDAC-IN-1 demonstrates cytotoxicity against various human cancer cells, induces cell cycle arrest in the G2 M phase, and triggers cell apoptosis, making it valuable for studying hematologic and solid tumors, including neuroblastoma and leukemia [1].
- $1,520
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