Mollicellin H, a secondary metabolite from the fungus C. brasiliense, exhibits an array of biological activities such as immunomodulation, cytotoxicity, and anti-tumor properties. It demonstrates growth inhibitory effects (GI 50 s) on various human cell lines, including breast cancer (Bre04) at 5.1 μg/mL, lung (Lu04) at 6.5 μg/mL, and neuroma (N04) at 2.5 μg/mL [1].

Glochidonol exhibits strong inhibitory effects against three human tumor cell lines, MCF-7, NCI-H-460 and SF-268, the GI(50) values of 9.0 +/- 3.7, 4.9 +/- 0.2 and 9.8 +/- 0.5, respectively; it also exerts its antiproliferative activity through the involv

Ardisiacrispin A (Deglucocyclamin) has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule.Ardisiacrispin(A+B) exhibit prominent abilities to inhibit the proliferation of HL-60 cells by blocking the cell cycle at S phase and inducing apoptosis.

Glutinol acetate shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17.9microM; it also has anti-inflammatory effect, exhibits moderate inhibitory activity of TNF-alpha secretion in the lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cell line.

Anserinone B, a benzoquinone with antifungal and antibacterial properties, inhibits radial growth by 50% and 37% against S. fimicola and A. furfuraceus, respectively. Additionally, it demonstrates moderate cytotoxicity across the National Cancer Institute's 60 human tumor cell lines, with a GI 50 value of 4.4 µg/mL.