hbc

HBC (HBC 530) 530 is a mimic of green fluorescent protein (GFP) fluorophore for imaging RNA in live cells. Fluoresces when bound to Pepper aptamer; displays high affinity binding (Kd = 3.5 nM). Suitable for confocal and two-photon microscopy. Confocal excitation maximum = 488 nm, emission maximum= 495 - 595 nm. Two-photon excitation maximum = 976 nm, emission maximum= 475 - 575 nm.

HBC620 shows brightly fluoresced in the Pepper bound state and can be visualize RNA dynamics in live cells. HBC620 is a HBC-like fluorophore.

HBC525, an HBC-like fluorophore with a dissociation constant (Kd) of 3.8 nM, serves as a fluorogenic RNA aptamer. It can be employed as fusion tags for imaging and tracking specific cellular RNAs. Additionally, this compound has been utilized in the creation of dynamic RNA nanodevices for the detection and imaging of cellular targets [1] [2].

HBC514, a nonfluorescent HBC-analog, emits strong green fluorescence upon forming a tight complex with Pepper RNA aptamer.

HBC599 is an HBC-like fluorophore. HBC599 shows brightly fluoresced in the Pepper bound state and can be visualized RNA dynamics in live cells.