liliaceae

Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one of the first sapogenins to be identified, and the first spirostan steroid to be identified as such.

1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxidant activity, can reduce neuronal oxidative damage and protect hepatocytes against oxidative stress and mitochondrial dysfunction, which may be associated with activation of Nrf2.

Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV （IC50=1 μg/mL） and EV71（IC50=0.33 μg/mL ）.

Yibeinoside A (Sinpeinine-3-O-β-glucoside) is an alkaloid from Fritillaria pallidiflora.

1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Peimisine can attenuate lung tissue injury( ALI), LDH and MDA amount in ALI mice in a dose dependent manner, it also lower the total protein, total white blood cells, lymphocyte and neutrophilic leukocyte in bronchoalveolar lavage fluid( BALF); suggests that peimisine can play a protective role against LPS-induced acute lung injury. 3. Peimisine has the protective effect on the experimental hepatic fibrosis formation, the possible mechanisms are associated with inhibiting fibrogenesis and fibrosis accumulation, and decreasing lipid peroxidation. 4. Peimisine can inhibit angiotensin I converting enzyme activity in a dose-dependent manner, displaying 5 % inhibitory concentration values of 526.5 microM, thus, it may have antihypertensive action.

1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.

Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.

1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.

Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.

Monocrotaline (Crotaline) is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes is noted after oral magnesium treatment.

Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.

Anemarrhenasaponin III is a natural product

Pennogenin steroidal saponins could be utilized to develop anticancer medicines.

Cymarin is a natural product for research related to life sciences. The catalog number is TN3746 and the CAS number is 508-77-0.

(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside is a natural product

17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax.

7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome.

Shatavarin IV shows in vitro anti-malassezia activity. Shatavarins (containing shatavarin IV) rich fraction (AR-2B) exhibits significant anticancer activity in both in vitro and in vivo experimental models.

Pseudojervine (O-beta-D-Glucopyranosyljervine) is derived from Veratrum nigrum L. Pseudojervine exhibits feeble inhibition activity against platelet aggregation.

Imperialine 3-β-D-glucoside (Sipeimine-3-beta-D-glucoside) is a natural product. Imperialine 3-β-D-glucoside may exhibit anti-tumor properties against multi-drug resistant tumor cells.

Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly

Polyphyllin E has synergistic anticancer effects.

2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4′-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antioxidant activity on DPPH with IC50 of 10.57 ug/mL.

Ophiopogonin A is a natural product

Saponin C from Liriope muscari can be extracted from Liriope muscari, family Liliaceae, has antithrombotic activity and induces autophagy.

OJV-VI is a natural product found in ophiopogonis.

2,3-Dimethoxybenzaldehyde (5,6-Dimethoxybenzaldehyde) is a benzoic acid analog, with high Antifungal activity (MIC=2.5 mM). 2,3-Dimethoxybenzaldehyde could be used for the synthesis of berberine.

Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.

3-Hydroxy-4',5-dimethoxystilbene is a natural product of Dracaena, Liliaceae. The catalog number is TN2941 and the CAS number is 58436-29-6. 3-Hydroxy-4',5-dimethoxystilbene can be used as a reference standard.

3-(2,4-Dihydroxybenzyl)-5-hydroxy is a natural product for research related to life sciences. The catalog number is TN2848 and the CAS number is 149180-48-3.

Cixiophiopogon A is a natural product from Ophiopogon japonicus.

Veratrosine (Veratramine-beta-D-glucoside) is an alkaloid isolated from the herbs of Veratrum nigrum. Veratrosine exhibits feeble inhibition activity against platelet aggregation.

(-)-Epipinoresinol is a natural product

7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 7,4'-Dihydroxy-8-methylflavan also has free radical scavenging properties.

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product, and has good pharmacological effects on the cardiovascular system.

Regaloside D is a natural product isolated from Lilium Longiflorum.

Anemarsaponin E is a nartural product from salt Anemarrhenae Rhizoma.

Polyphyllin F is a natural product of Paris, Liliaceae. The catalog number is TN4815 and the CAS number is 76296-74-7. Polyphyllin F can be used as a reference standard.

Polyphyllin C is a natural product

6-Aldehydo-isoophiopogonone A is a natural product of Ophiopogon, Liliaceae. The catalog number is TN5470 and the CAS number is 112500-90-0. 6-Aldehydo-isoophiopogonone A can be used as a reference standard.

D-Asparagine (H-D-Asn-OH) is a source of nitrogen for yeast strains. D-Asparagine is a competitive inhibitor of L-Asparagine hydrolysis (Ki = 0.24 mM).

Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.

1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.

3,9-Dihydroxypterocarpan and phaseollidin are all good precursors of the pterocarpan phytoalexin phaseollin.

De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects on induced NO production. De-O-methyllasiodiplodin effectively lowers the blood glucose level in d

Panasenoside is a natural product

Kaempferol-4'-O-beta-D-glucopyranoside is an antihypertensive agent.

Anemarrhena B is a natural product for research related to life sciences. The catalog number is TN3413 and the CAS number is 1627521-95-2.

Timorsaponin C is a natural product

Ophiopogonin B has antitumor activity and is a prospective inhibitor of PI3K/Akt.