Neamine tetrahydrochloride is a broad-spectrum aminoglycoside antibiotic, a degradation product of neomycin. Neamine tetrahydrochloride exerts its anti-angiogenic effects by targeting angiogenin. Neamine tetrahydrochloride has antibacterial, antitumor and neuroprotective activities.

Neamine, a broad-spectrum aminoglycoside antibiotic derived from Neomycin, exhibits potent antibacterial, antitumor, and neuroprotective activities. As an anti-angiogenesis agent, it specifically targets angiogenin [1] [2].