collagen a-1(iii) chain

Collagen proline hydroxylase inhibitor-1 exhibits antifibroproliferative activity.

8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+/K+ ATPase inhibitor with IC50 of 0.38μM.

VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)

This is a peptide inhibitor of collagen fibrillar matrix assembly.

Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide implicated in melanoma cell adhesion and critical for the development of the chicken peripheral nervous system [1] [2].

Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Collagen-IN-1 effectively reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelets. This compound holds promise for research into platelet-related thrombosis diseases [1].

Hydrocarbon chain derivative 1 has inhibitory activities against lipid synthesis.

This peptide is a fragment of the alpha-chain of insulin amino acids 1 to 13. The insulin a-chain epitope recognized by human T cells is posttranslationally modified.

Complex III-IN-1 (Compd 4c-2) is an inhibitor of complex III with antifungal activity. The EC50 value of Complex III-IN-1 against sclerotinia sclerotiorum is 18.53 mg/L [1].

Bis[2-(1-isoquinolinyl-N)phenyl-C](2,4-pentanedionato-O2,O4)iridium(III) is a useful organic compound for research related to life sciences. The catalog number is T67275 and the CAS number is 435294-03-4.

NC-III-49-1 is a potent bivalent bromodomain and extraterminal domain (BET) inhibitor with significant affinity for several BRD4 and BRDT isoforms, demonstrated by its Kd values of 0.095 nM for BRD4-1, 0.32 nM for BRD4-2, 0.29 nM for BRD4-T, 0.089 nM for BRDT-1, 5.5 nM for BRDT-2, and 0.058 nM for BRDT-T. Additionally, NC-III-49-1 exhibits antiproliferative effects and reduces the expression of c-Myc [1].