dynorphin a (1 8)

E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid receptor (KOR) agonist [1].

Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.

T-cell clones specific for this NY-BR-1 p904 A2 acetate(347142-73-8 free base) can recognize breast tumor cells expressing NY-BR-1.

Porcine dynorphin A(1-13) acetate (Dynorphin A Porcine Fragment 1-13 acetate) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.

Dynorphin B (1-13) acetate acts as an agonist on opioid κ-receptor.

RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, eject

BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell proliferation in v

Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.

Dynorphin B (1-13), a 13 amino acid, is an extraordinarily potent opioid peptide.

[DPro10] Dynorphin A (1-11), porcine, an N-Alkylated derivative, serves as a potent κ-opioid receptor agonist with a Ki value of 0.13 nM, exhibiting analgesic properties [1] [2].

Caspase-8-IN-1 is a potent caspase-8 inhibitor [1] .

Dynorphin A (1-13) amide, an endogenous opioid peptide, counteracts the analgesic effects of morphine [1].

α-Bag Cell Peptide (1-8) is an NH2-terminal fragment of α-bag cell peptide that inhibits LUQ (left upper quadrant) neurons and the depolarization of bag cells [1].

Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist [1] for the vasoactive intestinal peptide 1 (VIP 1) receptor.

[K15,R16,L27]VIP(1-7)/GRF(8-27), a selective agonist for the VIP 1 receptor, demonstrates binding IC 50 values of 2 nM for the human VIP 1, 1 nM for the rat VIP 1, and 30,000 nM for the rat VIP 2 receptors, respectively [1]. VIP stands for VASOACTIVE Intestinal Polypeptide.

[DAla2] Dynorphin A (1-9) (porcine) is a dynorphin utilized in research related to analgesic, addiction, and depression studies.

Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds in the transmembrane domain of the κ-receptor.

[K15,R16,L27]VIP(1-7)/GRF(8-27) (acetate) is an acetate salt form of the peptide [K15,R16,L27]VIP(1-7)/GRF(8-27). This compound acts as a selective agonist for the VIP 1 receptor, displaying IC50 values of 2 nM for human VIP 1, 1 nM for rat VIP 1, and 30,000 nM for rat VIP 2 receptors [1]. The peptide's acronym, VIP, stands for Vasoactive Intestinal Polypeptide.

Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, interacts with κ-opioid receptor's extracellular loop 2 and inhibits NMDA-activated currents with an IC 50 of 42.0 μM.

[DAla2] Dynorphin A (1-13), amide (porcine) is a peptide that potentially acts as a κ opioid receptor agonist. It is used in the research of the nervous system [1].

α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin. α-Neoendorphin is an endogenous opioid peptide and is a part for the neoendorphins which are a group of endogenous opioid peptides derived from the proteolytic c

Dynorphin A (1-10), an endogenous opioid neuropeptide, interacts with the κ-opioid receptor by binding to its extracellular loop 2 and inhibits NMDA-activated current, demonstrating an IC50 value of 42.0 μM.

[DPro10] Dynorphin A (1-11), porcine hydrochloride, is an N-alkylated derivative and a potent κ-opioid receptor agonist, exhibiting a K i value of 0.13 nM. This compound possesses analgesic properties [1] [2].

Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analog to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is us

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acut

Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .

[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD), a dynorphin1-13 (DYN) derivative extracted from porcine pituitary, exhibits high potency at peripheral opioid receptors GPI and MVD. Despite rapid in vivo degradation of DYN, this compound shows increased resistance to enzymatic cleavage, enhancing its stability against peptide-degrading enzymes [1].

Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.

Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selective cysteine peptidase inhibitor [1].