ecteinascidin-analog-1

Ecteinascidins are a family of tetrahydroisoquinoline alkaloids known for their antitumor and antimicrobial activities. [Ecteinascidin-Analog-1] is a valuable intermediate for the synthesis of Ecteinascidin analogues.

CE3F4 analog 1 is an analogue of CE3F4. It is a chemical compound utilized in various [scientific applications] due to its unique properties, notably in (radical scavenging) and (oxidation-reduction) processes. It plays a significant role in advanced (catalysis), (pharmaceutical) research, and (material science) due to its stability and reactivity.

LY88074 analog 1, a benzothiophene compound with nitrogen-containing non-basic side chains, can be utilized either independently or alongside estrogen or progestin. This agent is effective for mitigating post-menopausal symptoms, including osteoporosis, cardiovascular-related pathological conditions, and estrogen-dependent cancer.

Dasatinib analog-1 (compound 5826) demonstrates inhibition of CYP3A4 activity, presenting a K_i value of 5.4 μM, and effectively prevents the formation of glutathione adducts [1].

Cryptophycin analog 1, an ADC payload, exhibits anticancer activity and demonstrates cellular potency an order of magnitude greater than the approved ADC payloads MMAE and DM1 [1].

[Leu27]-Melan-A, MART-1 (26-35), is a biologically active peptide modified by substituting leucine for alanine at position 27, which enhances its HLA-A*0201 binding, immunogenicity, and antigenicity compared to the natural peptide. Pyroglutamyl (pGlu) peptides, arising from the spontaneous cyclization of glutamine (Q) or glutamic acid (E) at the N-terminus, are a recognized subset of peptides that may confer increased stability due to the hydrophobic γ-lactam ring of pGlu. These pGlu peptides are typically included during peptide purity assessments in HPLC analysis.

Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.

COH34 analog 1 is a COH34 oxidation analogue that can be used to synthesize active compounds.

Thiamine diphosphate analog 1, an analog of Thiamine diphosphate (the active form of vitamin B1 and a universal cofactor in key cellular pathways), mirrors the structure and potentially the function of its prototype.

ML120 analog 1 (compound 1) acts as a competitive inhibitor of Hematopoietic protein tyrosine phosphatase (HePTP), exhibiting a K i value of 0.69 μM [1].

DB04760 analog 1 is an analogue of DB04760.

Liproxstatin-1 analog is a potent ferroptosis inhibitor, derived from liproxstatin-1 with a similar structure. It effectively inhibits ferroptotic cell death, with an IC50 value of 22 nM.

Resveratrol analog 1, an analog of Resveratrol, is a natural polyphenolic phytoalexin with antioxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.