protease-activated receptor-3 (par-3) , human

TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA, is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3) [1].

2-Amino-3-(2-chlorophenyl)propanoic acid (2-Chloro-DL-Phenylalanine) is a phenylalanine derivative involved in biometabolism.

Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Rac1 Inhibitor W56 acetate(1095179-01-3 free base) selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.

CREBtide acetate is a synthetic substrate for PKA (Km=3.9 μM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).

HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.

RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist. Increases intracellular Ca2+ levels in cells expressing CB1 receptors in vitro. Also high affinity CB2 positive allosteric modulator (Ki

3X FLAG peptide TFA (402750-12-3 free base) (3X FLAG peptide TFA) is a synthetic peptide of 23 amino acid residue. The Asp-Tyr-Lys-Xaa-Xaa-Asp motif is repeated three times in the peptide.

Selank Acetate is a typical anxiolytic producing no side effects.

Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.

AOD9604 acetate(221231-10-3 free base) is a potential anti-obesity peptide based on the human growth hormone.

Acetyl tetrapeptide-3 Acetate is a biomimetic peptide.

TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signaling.

CEF3 acetate corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.

ACTH 1-14 acetate(25696-21-3 free base) (Adrenocorticotropic Hormone Fragment 1-14 acetate) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress.

γ-1-MSH, amide acetate (72629-65-3 free base), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v.

Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats.

LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.

Peptide YY (PYY) (3-36), human (Peptide YY (3-36)), is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.

SN50 acetate is a cell permeable inhibitor of NF-κB translocation.

Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.

Hemorphin-7 acetate is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE).

Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].

b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.

Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 with an IC50 of 10.4 M.

(2R,3S)-3-Phenylisoserine hydrochloride serves as a pharmaceutical intermediate.

Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).

(S)-3-Thienylglycine is a thiophene derivative and can be used to investigate the genotoxicity of the similar structures with thiophene derivatives.

Exendin-3 4 (64-86) is a polypeptide composed of a specific amino acid sequence within the exendin-3 or exendin-4 peptide chains.

DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.

Palmitoyl Tetrapeptide-3 (Rigin) (Rigin) is a synthetic peptide, corrspending to 341-344 amino acid sequence of IgG human H-chain, with phagocytosis stimulating activity.Palmitoyl Tetrapeptide-3 stimulates expression of GCP-2 (Granulocyte Chemotactic Protein), which is a chemotactic protein that can recruit cells involved in the preparation and cleansing of the site, to damaged areas.

N-Boc-3-Hydroxy-L-Tyrosine methyl ester, with catalog number T66564 and CAS number 37169-36-1, is a valuable organic compound for life sciences research.

(R)-2-Amino-3-(3-nitrophenyl)propanoic acid is a valuable organic compound for life sciences research, catalog number T65799, CAS number 169530-97-6.

Lynronne-3, an antimicrobial peptide, demonstrates activity against Gram-positive bacteria, including multi-drug resistant (MDR) strains, with a minimum inhibitory concentration (MIC) ranging from 32-128 μg/mL for methicillin-resistant Staphylococcus aureus (MRSA) strains. Additionally, Lynronne-3 is efficacious in combating Pseudomonas aeruginosa infections [1].

Pentapeptide-3, a pentapeptide fragment derived from waglerin-1 neurotoxin, is sourced from Temple Viper venom. This compound serves as a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), blocking nerve signals at the post-synaptic membrane. Notably, Pentapeptide-3 exhibits anti-aging properties and is commonly incorporated with other cosmetic peptides for enhanced effects [1] [2].

Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmol/kg to an ob/ob mouse diabetes model, GIP-1 (3-42) elevates plasma glucose levels and lowers plasma insulin levels, demonstrating its effect on reducing insulin secretion from BRIN-BD11 pancreatic cells at a concentration of 100 nM.

Histatin 3, a salivary antimicrobial peptide, exhibits activity against C. albicans with an LC50 of 9.2 µM. Additionally, at a concentration of 12 µM, it promotes actin polymerization in cell-free assays.

(2S,3R)-3-(Benzyloxy)-2-(((benzyloxy)carbonyl)amino)butanoic acid is a useful organic compound for research related to life sciences. The catalog number is T64756 and the CAS number is 69863-36-1.

(S)-2-Amino-3-(2-(trifluoromethyl)phenyl)propanoic acid is a valuable organic compound used in life sciences research. It is identified by catalog number T66652 and CAS number 119009-47-1.

Boc-D-Phe(3-F)-OH is a useful organic compound for research related to life sciences. The catalog number is T65692 and the CAS number is 114873-11-9.

Fmoc-Phe(3-Cl)-OH is an amino acid derivative and has a wide range of applications in life science related research.

(S)-2-Amino-3-cyclopropylpropanoic acid is an invaluable organic compound for life sciences research. It can be identified using catalog number T67668 and CAS number 102735-53-5.

3-Chloro-L-alanine Hydrochloride (catalog number T67574, CAS number 51887-89-9) is a valuable organic compound for life sciences research.

2-Amino-3-mercaptopropanoic acid hydrochloride xhydrate (catalog number: T66879, CAS number: 96998-61-7) is a valuable organic compound for life sciences research.

(R)-3-Amino-4-(benzyloxy)-4-oxobutanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66671 and the CAS number is 79337-40-9.

ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat), the fragment spanning amino acids 3-24 of adrenocorticotropic hormone (ACTH), serves as a research tool in studying illnesses such as cancer, immune diseases, and cardiovascular disease [1].

3-Hydroxybutyrate dehydrogenase (3-HBDH), a mitochondrial enzyme, plays a crucial role in the metabolism of ketone bodies and butanoate, catalyzing the conversion of (R)-3-hydroxybutanoate into acetoacetate [1]. This enzyme is frequently utilized in biochemical studies due to its involvement in both the synthesis and degradation of key metabolic substances.

(S)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoate is a useful organic compound for research related to life sciences. The catalog number is T66724 and the CAS number is 1872-59-9.