T3S0195 |
Nootkatone
|
4674-50-4
|
99.04%
|
|
1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent o...
|
T0800 |
Danthron
|
117-10-2
|
99.03%
|
|
Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
|
T3546 |
STO-609
|
52029-86-4
|
98.95%
|
|
STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL)....
|
T5S2361 |
Epiberberine
|
6873-09-2
|
98.95%
|
|
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
|
TN1990 |
Norathyriol
|
3542-72-1
|
98.93%
|
|
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
|
T6146 |
Dorsomorphin dihydrochloride
|
1219168-18-9
|
98.89%
|
|
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on s...
|
TN2179 |
Saponarin
|
20310-89-8
|
98.84%
|
|
Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver damage.
|
T6285 |
GSK-690693
|
937174-76-0
|
98.78%
|
|
GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
|
T2854 |
Phillyrin
|
487-41-2
|
98.76%
|
|
Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking...
|
T5497 |
AMAROGENTIN
|
21018-84-8
|
98.75%
|
|
Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell ...
|
T19661 |
8-Chloroadenosine
|
34408-14-5
|
98.75%
|
|
8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine acti...
|
T7955 |
EB-3D
|
1839150-63-8
|
98.75%
|
|
EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.
|
T2468 |
A-769662
|
844499-71-4
|
98.72%
|
|
A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).
|
T8476 |
RSVA405
|
140405-36-3
|
98.71%
|
|
RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
|
T9219 |
WH-4-025
|
1876463-35-2
|
98.7%
|
|
WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.
|
T5187 |
MK-3903
|
1219737-12-8
|
98.63%
|
|
MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).
|
T11947 |
MARK4 inhibitor 1
|
2271081-58-2
|
98.59%
|
|
MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (M...
|
T4S0800 |
Demethyleneberberine
|
25459-91-0
|
98.54%
|
|
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either ...
|
T5162 |
MRT67307 HCl (1190378-57-4(free base))
|
T5162
|
98.52%
|
|
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).
|
T6129 |
GSK-1070916
|
942918-07-2
|
98.51%
|
|
GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the ...
|