COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.

Cat. No.	Product name	CAS No.	Purity
T1376	2-Amino-5-methyl-3-thiophenecarbonitrile	138564-58-6	99.33%
T1376	2-Amino-5-methyl-3-thiophenecarbonitrile is commonly used in the synthesis of Olanzapine.
T27335	Floctafenine	23779-99-9	99.31%
T27335	Floctafenine (R-4318) is an orally available nonsteroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor and interferes with the antiplatelet eff...
T5460	Mofezolac	78967-07-4	99.29%
T5460	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000
T0458	Indomethacin	53-86-1	99.27%
T0458	Indomethacin (Indometacin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of indomethacin is as a Cyclooxygenase Inhibitor.
T1467	Acemetacin	53164-05-9	99.26%
T1467	Acemetacin (TVX 1322) is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose a...
T4A2456	Gamabufotalin	465-11-2	99.24%
T4A2456	1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable ...
T6497	Fenoprofen Calcium	34597-40-5	99.24%
T6497	Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
T5430	[8]-Shogaol	36700-45-5	99.24%
T5430	[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.
T3417	Amentoflavone	1617-53-4	99.22%
T3417	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for ...
T25253	Cinnamtannin B-1	88082-60-4	99.22%
T25253	Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeyl...
T7052	Gnetol	86361-55-9	99.21%
T7052	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly sup...
T0855	(R)-Naproxen	23979-41-1	99.2%
T0855	(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dy...
T3342	Xanthohumol	6754-58-1	99.18%
T3342	Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated...
T3682	(-)-Catechin gallate	130405-40-2	99.18%
T3682	(-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of 6PGD, IDH. (-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of human Be...
T12580	PTUPB	1287761-01-6	99.15%
T12580	PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
T6S0077	Byakangelicol	26091-79-2	99.15%
T6S0077	1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; t...
T6387	Ampiroxicam	99464-64-9	99.15%
T6387	Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
T0399	Methyl salicylate	119-36-8	99.13%
T0399	Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain...
T2878	Ginsenoside Rd	52705-93-8	99.13%
T2878	Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.
T7838	Losartan Carboxaldehyde	114798-36-6	99.12%
T7838	Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.