T16291 |
NF157
|
104869-26-3
|
98%
|
|
NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly s...
|
T16464 |
Pelubiprofen
|
69956-77-0
|
98%
|
|
Pelubiprofen, an orally active non-steroidal anti-inflammatory drug (NSAID) belonging to the 2-arylpropionic acid family, selectively inhibits COX-2 activity alo...
|
TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
T12227 |
Nimesulide D5
|
1330180-22-7
|
98%
|
|
Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM)
|
TN3410 |
Anatabine
|
581-49-7
|
98%
|
|
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheime...
|
TN4752 |
Perilloxin
|
263249-77-0
|
98%
|
|
Perilloxin possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 microM.
|
TN1171 |
6-Dehydrogingerdione
|
76060-35-0
|
98%
|
|
1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
|
T4131 |
Arjunic acid
|
31298-06-3
|
98%
|
|
Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values r...
|
TN3708 |
Coronarin D
|
119188-37-3
|
98%
|
|
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
|
TN1374 |
α-Chaconine
|
20562-03-2
|
98%
|
|
Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Al...
|
T11296 |
Flosulide
|
80937-31-1
|
98%
|
|
Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
TN1606 |
(-)-Epiafzelechin
|
24808-04-6
|
98%
|
|
(-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX acti...
|
T15345 |
FR-188582
|
189699-82-9
|
98%
|
|
FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).
|
TN1062 |
Peonidin chloride
|
134-01-0
|
98%
|
|
Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast c...
|
TN1143 |
1-O-Acetyl britannilactone
|
681457-46-5
|
98%
|
|
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR...
|
TN1871 |
Ligustroside
|
35897-92-8
|
98%
|
|
Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustrosid...
|
TN1510 |
Clematomandshurica saponin B
|
916649-91-7
|
98%
|
|
Clematomandshurica saponin B shows significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.58 microM).
|
TN3805 |
Dehydrogeijerin
|
16850-91-2
|
98%
|
|
Dehydrogeijerin significantly inhibits the inflammatory activity of activated macrophages, suggesting that it could be a potential candidate for the treatment of...
|