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COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN3482 Bakkenolide B 18455-98-6 98%
Bakkenolide B
Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.
TN4062 Flavidin 83924-98-5 98%
Flavidin
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
T19886 Cirsilineol 41365-32-6 98%
Cirsilineol
Cirsilineol (Eupatrin) is isolated from the herb of Artemisia vestita Wall and shows immunosuppressive, anti-proliferative, and anti-tumor properties. Cirsilineo...
T16419 Oxyphenbutazone 129-20-4 98%
Oxyphenbutazone
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively...
TN2327 Zedoarondiol 98644-24-7 98%
Zedoarondiol
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs...
TN4582 Moracin T 1146113-27-0 98%
Moracin T
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
TN4748 Penduletin 569-80-2 98%
Penduletin
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
TN2534 1-Hydroxy-2,3,5-trimethoxyxanthone 22804-49-5 98%
1-Hydroxy-2,3,5-trimethoxyxanthone
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
TN4212 Hirsutanonol 41137-86-4 98%
Hirsutanonol
Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits ...
T11169 Eicosatetraynoic acid 1191-85-1 98%
Eicosatetraynoic acid
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygen...
TN4463 Lupeolic acid 87355-32-6 98%
Lupeolic acid
Lupeolic acid has anti-inflammatory activity.
TN4064 Flavoglaucin 523-73-9 98%
Flavoglaucin
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
TN1755 Hyperforin 11079-53-1 98%
Hyperforin
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
T11660 Insulin levels modulator 1019254-94-4 98%
Insulin levels modulator
Insulin level regulators can be used to treat diabetes.
TN4783 Picralinal 20045-06-1 98%
Picralinal
Picralinal has anti-inflammatory and analgesic effects.
TN4489 Manassantin A 88497-87-4 98%
Manassantin A
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
TN5149 Tirotundin 56377-67-4 98%
Tirotundin
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
TN4860 Pueroside B 100692-54-4 98%
Pueroside B
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
TN3839 Desoxo-narchinol A 53859-06-6 98%
Desoxo-narchinol A
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity agains...
TN2223 Soyacerebroside I 114297-20-0 98%
Soyacerebroside I
Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity.
Bakkenolide B
TN3482
Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.
Flavidin
TN4062
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
Cirsilineol
T19886
Cirsilineol (Eupatrin) is isolated from the herb of Artemisia vestita Wall and shows immunosuppressive, anti-proliferative, and anti-tumor properties. Cirsilineo...
Oxyphenbutazone
T16419
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively...
Zedoarondiol
TN2327
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs...
Moracin T
TN4582
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
Penduletin
TN4748
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
1-Hydroxy-2,3,5-trimethoxyxanthone
TN2534
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
Hirsutanonol
TN4212
Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits ...
Eicosatetraynoic acid
T11169
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygen...
Lupeolic acid
TN4463
Lupeolic acid has anti-inflammatory activity.
Flavoglaucin
TN4064
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
Hyperforin
TN1755
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
Insulin levels modulator
T11660
Insulin level regulators can be used to treat diabetes.
Picralinal
TN4783
Picralinal has anti-inflammatory and analgesic effects.
Manassantin A
TN4489
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
Tirotundin
TN5149
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
Pueroside B
TN4860
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
Desoxo-narchinol A
TN3839
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity agains...
Soyacerebroside I
TN2223
Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity.
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TargetMol