TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4446 |
Longiferone B
|
1639810-67-5
|
98%
|
|
Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression.
|
T10152L |
4-Methylamino antipyrine hydrochloride
|
856307-27-2
|
98%
|
|
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibit...
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
TN3922 |
Effusanin E
|
76470-15-0
|
98%
|
|
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
|
TN4586 |
Mulberrofuran A
|
68978-04-1
|
98%
|
|
Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy...
|
TN4584 |
Morolic acid
|
559-68-2
|
98%
|
|
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent change...
|
T17036 |
Tenidap
|
120210-48-2
|
98%
|
|
Tenidap is a non-steroidal anti-inflammatory drug and is a selective COX-1 inhibitor (IC50: 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively). Tenidap is als...
|
TN5019 |
Siegeskaurolic acid
|
52645-97-3
|
98%
|
|
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via...
|
T13263 |
COX/5-LO-IN-1
|
154355-75-6
|
98%
|
|
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
|
TN4879 |
Questinol
|
35688-09-6
|
98%
|
|
Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit th...
|
TN3070 |
4beta-Hydroxywithanolide E
|
54334-04-2
|
98%
|
|
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
|
T4S1616 |
Sanggenon D
|
81422-93-7
|
98%
|
|
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
|
T15630 |
Tilmacoxib
|
180200-68-4
|
98%
|
|
Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).
|
T15449 |
GW-406381
|
221148-46-5
|
98%
|
|
GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats followin...
|
TN4162 |
Goshonoside F5
|
90851-28-8
|
98%
|
|
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
|
TN3810 |
Dehydroperilloxin
|
263241-09-4
|
98%
|
|
Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM.
|
T12419 |
PF-04634817 succinate
|
2140301-98-8
|
98%
|
|
PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.
|
TN4581 |
Moracin D
|
69120-07-6
|
98%
|
|
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
|
TN1562 |
Dehydromiltirone
|
116064-77-8
|
98%
|
|
Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF...
|