COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.

Cat. No.	Product name	CAS No.	Purity
T1432	Phenylbutazone	50-33-9	99.92%
T1432	Phenylbutazone (Butazolidine) is a butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ankylo...
T1582	Naproxen	22204-53-1	99.91%
T1582	Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activ...
T1133	Nimesulide	51803-78-2	99.91%
T1133	Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.
T1780	Parecoxib	198470-84-7	99.90%
T1780	Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
T1558	Resveratrol	501-36-0	99.9%
T1558	Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targe...
T1562	Rebamipide	90098-04-7	99.9%
T1562	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which re...
T4403	AX-024 hydrochloride	1704801-24-0	99.9%
T4403	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
T0826	Meloxicam	71125-38-7	99.89%
T0826	Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification ...
T0219	Valdecoxib	181695-72-7	99.89%
T0219	Valdecoxib (SC 65872) is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It i...
T1555	Diclofenac sodium	15307-79-6	99.89%
T1555	Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium s...
T5843L	(S)-Flurbiprofen	51543-39-6	99.88%
T5843L	Esflurbiprofen is an inhibitor of COX-1 and COX-2.
T2550	Tolmetin	26171-23-3	99.88%
T2550	Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification o...
T7596	Firocoxib	189954-96-9	99.87%
T7596	Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
T0424	Bismuth Subsalicylate	14882-18-9	99.87%
T0424	Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion...
T1574	Etoricoxib	202409-33-4	99.87%
T1574	Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib ...
T0456	Cinchophen	132-60-5	99.87%
T0456	Cinchophen (Cinconal), an analgesic drug, is utilized in treating gout.
T1544	Olsalazine disodium	6054-98-4	99.86%
T1544	Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
TN7025	Canolol	28343-22-8	99.86%
TN7025	Canolol (Phenol, 4-ethenyl-2,6-dimethoxy-) is an antioxidant phenolic compound that has potential use as a COX-2 inhibitor.
T4313	Tinoridine hydrochloride	25913-34-2	99.86%
T4313	Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependen...
T8656	CAY10404	340267-36-9	99.85%
T8656	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and M...