COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.

Cat. No.	Product name	CAS No.	Purity
TN1040	Skullcapflavone II	55084-08-7	99.78%
TN1040	Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavon...
T6893	MK-886	118414-82-7	99.78%
T6893	MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagoni...
TQ0169	Inulicin	33627-41-7	99.77%
TQ0169	Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK.
T4S0590	Columbin	546-97-4	99.74%
T4S0590	1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC...
T6S1538	Neochlorogenic acid	906-33-2	99.73%
T6S1538	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T15577	Indobufen	63610-08-2	99.73%
T15577	Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxa...
T3214	NS-398	123653-11-2	99.72%
T3214	NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.
T2826	Asaraldehyde	4460-86-0	99.72%
T2826	Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1.
T2732	(-)-Epicatechin gallate	1257-08-5	99.72%
T2732	(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins...
T0858	Flufenamic acid	530-78-9	99.71%
T0858	Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
T1421	Aceclofenac	89796-99-6	99.71%
T1421	Aceclofenac (Preservex) is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties.
T1394	Ibuprofen	15687-27-1	99.7%
T1394	Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibupro...
T4561	Tiaprofenic acid	33005-95-7	99.69%
T4561	Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
T23046	N-tert-butyl-α-Phenylnitrone	3376-24-7	99.69%
T23046	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-...
T8255	(±)-Catechin	7295-85-4	99.69%
T8255	(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.
T6540	Ibuprofen Lysine	57469-77-9	99.66%
T6540	Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.
T2403	Bromfenac sodium hydrate	120638-55-3	99.65%
T2403	Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analg...
T5S0045	Isofraxidin	486-21-5	99.65%
T5S0045	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has...
T3811	Ginsenoside C-K	39262-14-1	99.65%
T3811	Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.
T8356	FPL 62064	103141-09-9	99.64%
T8356	FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetas...